Without prospective trials to guide management, NCCN also recommends consideration of radiation therapy (XRT). According to NCCN guidelines wide excision means excision with the intention of obtaining surgical margins ≥1 cm. INTRODUCTION: National Comprehensive Cancer Network (NCCN) guidelines recommend wide excision without axillary staging to treat phyllodes tumors of the breast. The National Comprehensive Cancer Network (NCCN ) makes no representations or This follows the same breast cancer follow up protocol defined by NCCN guidelines. Phyllodes tumors (FILL-odes or full-OH-deez) can also be spelled phylloides tumors (full-OY-deez). Additionally, they recommend cautious use of radiotherapy, particularly in young patients. These are rare breast tumors that start in the connective (stromal) tissue of the breast. DCIS-1 Current guidelines for phyllodes tumor recommend against axillary dissection and chemotherapy use. Exact extent of clearance under debate, currently no consensus as to adequate margin width, while 10 mm is generally considered acceptable (NCCN Guidelines: Breast Cancer - Phyllodes Tumor [Accessed 2 July 2020], Ann Surg Oncol 2019;26:2747) Axillary dissection not indicated Available at: www.nccn.org (Accessed on February 22, 2016). Grabowski J, Salzstein SL, Sadler GR, Blair SL. Am Surg 2007; 73:967. Version 2.2016. Updates in Version 2.2016 of the NCCN Guidelines for Breast Cancer from Version 1.2016 include: Phyllodes tumors are most common in women in their 40s, but women of any age can have them. Those with an associated invasive cancer should undergo adjuvant systemic therapy based on the stage and hormone receptor status, as outlined online, in these guidelines, at www.NCCN.org . The median follow up was 11 months with a range of 4-33 months. NCCN Clinical practice guidelines in oncology (NCCN Guidelines). NCCN Guidelines for the Management of Phyllodes Tumor. Locally recurrent breast mass following excision of phyllodes tumor Metastatic disease 1 Pathology should be reviewed to assess for fibroadenoma versus phyllodes (phyllodes benign, borderline and malignant). Patient management was examined using NCCN guidelines to determine the relative adherence of providers to established treatment recommendations . Updates in Version 1.2019 of the NCCN Guidelines for Breast Cancer from Version 4.2018 include: Continued UPDATES General: Recommendations for Lobular Carcinoma in Situ (LCIS-1) were removed from the NCCN Guidelines for Breast Cancer; see the NCCN Guidelines for Breast Cancer Screening and Diagnosis. Malignant phyllodes tumors: a review of 752 cases. malignant phyllodes tumor of the breast were followed up at 3 monthly intervals. 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